Mechanisms of Impaired Anticryptococcal Activity of Monocytes from Donors Infected with Human Immunodeficiency Virus

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Mechanisms of impaired anticryptococcal activity of monocytes from donors infected with human immunodeficiency virus.

The mechanisms by which monocytes from patients infected with human immunodeficiency virus (HIV) have reduced growth inhibitory activity against Cryptococcus neoformans was examined. Monocyte-enriched peripheral blood mononuclear cells from 12 HIV-seropositive donors with CD4 cell counts of 10-210 cells/mm3 (median, 85) and HIV-seronegative donors were compared in assays to determine the bindin...

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 1997

ISSN: 0022-1899,1537-6613

DOI: 10.1086/517284